>>> John Boone on Biofuzz
WE> Given a function f measured at discrete times t1, t2, ...,
WE> ti, ... with ti < ti' where i' = i+1, plot the pairs <
WE> f(ti), f(ti') >. So what's the spread function? A measure
JB> The spread function is the thousand dollar question and
JB> one I am still pondering. Something, more mathematical,
JB> "what is the minimum domain of the representation function
JB> (f(ti),f(ti')) such that the heart shows sufficient chaotic
JB> behavior?"
I would think the spread function would be a measure of distribution such as
standard deviation of the distances between all pairs of points.
WE> of what? The function of your example is 60/(Pulse
WE> Interval). Why the reciprocal?
JB> In response to "Why the reciprocal?" I assume by this
JB> why plot (f(ti),f(ti'))? It was arbitary and gleamed by
JB> the work of some in "Scientific American" four years ago.
But why plot 60/(Pulse Interval)? The 60 is most likely because of 1 minuet
= 60 seconds. But why not (Pulse Interval) directly or (Pulse Interval)/60?
JB> There are many other ways to represent the data.
JB> However, it a reasonable way to represent the data.
JB> If you look at a -simple- system of degree 2, pendulum
JB> with moving pivot point, the representation of the
JB> movement of pendulum as a function of time could be
JB> done by (P(ti),P(ti')).
(P(ti),P(ti')) and then (P(ti'),P(ti'')). This switch of ti to ti' defies my
ability to visualize just what is happening. This glib switching the x and y
axis indicates some conceptual symmetry I'm not grasping. Why the two
dimensional data display? Why not just calculate delta-f(t) = f(t') - f(t)
and take the standard deviation of the delta-f's?
JB> It seems reasonable to continue the method of
JB> representation with heart rate.
Don't get the pendulum example, too complex. How about a drummer, thump,
thump, thump or a typist, click, click, click.
JB> Ah, bingo, in healthy hearts, the pulse interval doesn't
JB> hold steady, but in fact is "choatic." Reason, the pulse
JB> interval is a representation of a multiple of excitable
JB> tissue or cells, in this case, the heart.
JB> IOW, the less "choatic" the heart the more unhealthy
JB> it is.
Hm, what about fibrillation and other erratic heart mummers? Aren't they
chaotic? A healthy person movements has a large plot domain while a dying
person movements has a shrinking plot domain.
WE> will all fall at about the same point. A -small- spread
WE> but a likelihood of death?
JB> We find that as the plot domain diminishes, the less spread,
JB> the more unhealthy the heart.
Plot domain? The smallest rectangle with sides parallel to the axis that
contains all the plotted points.
WE> Any fuzz in any of these magazines?
JB> Nope, the one I am currently reading, reentrant supraventricular
JB> tachycardia, fast heart beat.
JB> There doesn't seem to be much research in this area, perhaps,
JB> there doesn't seem to be an awareness or understanding of "fuzzy"
JB> or fractals.
I've heard it rumored some years ago that medical students are mathematical
shy. Is that so? Are you in medicine or biology? Are you considering a
fuzzy thesis or research proposal. Wish I could help you, but my fuzzy
background is scant. What you're considering would require understanding
application examples. BTW, do you have access to the SCIENCE fidonet echo?
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