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echo: philos
to: JOHN BOONE
from: WILLIAM ELLIOT
date: 1998-01-18 01:43:00
subject: Biofuzz

 >>> John Boone on Biofuzz 
 JB> If one were to measure HR, generated by measuring the P-P 
 JB> internal - the time from the beginning of one heart beat to 
 JB> the beginning of the next divided into 60) placing them in a 
 JB> sequence, with increasing number representing HR happening at 
 JB> a latter point in time, e.g. HR1, HR 2, HR 3 HR4, HR5, HR6, HR7, 
 JB> etc.  
 JB> Now, let x be HR1 and y be HR2 and plot the point, 
 JB> next let x by HR2 and y be HR3 and plot the point, etc. 
 JB> Said plotting technique results in a distribution on the 
 JB> x-y plane.  Apparently, the smaller the spread, the more 
 JB> likely death is to occur.  The trick becomes what spread 
 JB> is "Ok" and what spread is not. 
Given a function f measured at discrete times t1, t2, ..., ti, ... with ti < 
ti' where i' = i+1, plot the pairs .  So what's the spread 
function?  A measure of what?  The function of your example is 60/(Pulse 
Interval).  Why the reciprocal?
Now if the pulse interval is holding steady, the points will all fall at 
about the same point.  A -small- spread but a likelihood of death?  
 
 WE> Indeed, and visa versa, life like formations are generated by such a 
 WE> process. 
 JB> Even crystalization, shows such fractal nature. 
Yes, but even more.  Computer graphics generated by fractles are very life 
like.  Trees, ferns, etc, for example.
 WE> Now if you were to look into the index of your books,  
 WE> especially the one on managing uncertainty, for biological 
 WE> or medical applications, that would be a start. 
 JB> I have a book, differential equations and their applications 
 JB> with a look at the medical disorder diabetes, but have not had 
 JB> time to look at it like so many other books :(. 
Naw, not that book, your -fuzzy- books.  A quick look in one or two books 
just to locate, not to read, any examples.
 WE> uncertainty is frequent companion to diagnosis.  Let me 
 WE> know if you find any examples. 
 JB> Right, now, I have 5 magazines to read, just got 4 in the mail, 
 JB> so, it will be a while before I will be able to look and contemplate. 
 JB> I have tried to keep this short as I have some heavy reading to 
 JB> do. 
Any fuzz in any of these magazines?
... Is Occam's razor sharp enuf to split hairs?
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