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echo: grand_rounds
to: MACIEK BLACH
from: CATHY HETTINGER
date: 1996-05-21 11:26:00
subject: CJD Blood Disease

Maciek, I recently spent some time on Medline checking out stuff that 
mentioned CJD disease.  There was an article a few years back in scientific 
American on Prion diseases.  The theory is (not good proof for it) that prion 
diseases are very different from most other infectious diseases.  The protein 
seems to be able to replicate without the basic messenger genes-RNA or DNA. I 
recall a diagram in the article that shows how it could be done.  This prion 
may not be found to much of a degree in the blood, it resides in the brain.  
It may also be in the muscles as there is some evidence that Mad Cow disease 
could be transmitted from meat.  Because this illness is so different from 
viruses and bacteria I think it may well not be so much of a problem for a 
reduced immune system.  The recent concern with British beef stems from some 
known transmission of Scrapie from sheep through supplementing with sheep 
meat to other animals.   These are very slow illnesses, most case of CJD that 
occure sporadically are in older people.  They think if there is an epidemic 
in England it won't show up for ten or twenty years.  These are rare 
illnesses, there is no evidence they can be transmitted through the blood, 
and if prion diseases are as they say there is little reaction from the 
immune system anyway.  I don't think anyone would choose to have the exposure 
your daughter had, but there are probably worse things.  Good luck, Cathy.
--- Maximus 3.01
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* Origin: The Central Florida Psychology Forum BBS (1:363/52)

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