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echo: evolution
to: All
from: Joe Felsenstein
date: 2003-05-08 20:44:00
subject: Re: Evolution of a gene

In article ,
Eugene Kononov  wrote:
>Suppose you want to verify a biological/philosophical theory that the
>humans are imperfect because they still have a recessive gene that
>comes from incest between some close relatives of Adam and Eve. Assume
>also that it happened about 6,000 years ago. If you need an estimate
>of the number of generations in 6,000 years, take 250. According to
>the laws of genetic evolution (if there are any), what are the chances
>that this recessive gene is still in the current generation of people?
>
>I'll do the math myself, I just want to know some probabilistic
>formula/rule that a particular gene mutates (completely, partially?).

Alleles ("genes") do not arise because of inbreeding.  The inbreeding
simply makes them visible, when they were present in both parents beforehand.
So there cannot be any alleles that come from incest between any people.

So, in that sense, the answer is zero.

-- 
Joe Felsenstein         joe{at}removethispart.gs.washington.edu
 Department of Genome Sciences, University of Washington,
 Box 357730, Seattle, WA 98195-7730 USA
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