From: Alan Cairns 

On 29/12/03 7:11 AM, in article 3ff0439e$1{at}w3.nls.net, "Gary Britt"
 wrote:

> Alan, what is it that being misfolded causes the disease pathology, they
> cause RNA or DNA messengers to behave improperly or they cause enzymes to
> misbehave-behave?  What is the process by which normally folded proteins
> become misfolded in the presence of prions?


I am no prion expert. They have no effect on DNA or RNA. They are misfolded
proteins, which induce other surrounding proteins to misfold as well. These
proteins will cause disease if they are structurally necessary for neurons.

Alan

This week I will be reading up on prions. I may have more information later.

Alan

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