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| subject: | Re: rate of evolution |
"Daniel Sch?tz" wrote
>
> because I want to take a look how mutation rate, generation time an
> selection pressure interacts with the rate of evolution (evolution
> velocity) I need different measurements:
>
> * generation times of any species
> * mutation rates of any species and
> * the number of species in a population that came to reproduction and
> the number of the reproducted organism that also came to reproduction.
> With this two data I can calculate the selection pressure as the ratio
> of (number of reproducters)/(number of childs that also came to
> reproduction).
>
> If you could give me some of needed information I would be very happy.
>
It gets very complicated. The most important thing you need to know is
probably that evoution is measured in generations, so generation time gives
a linear response.
The next most important thing is the selection coefficient, s, of a new
mutation. The most fit genotype is assumed to have a fitness of 1, so other
genotypes have fitness of less than one, and s is basically the difference
between the most fit genotype and the least fit genotype. The chance of an
advantageous mutation being fixed is 2s, regardless of the size of the
population (beyond a certain minimum of course).
The problem is that if the mutation rate is too high then drift will
dominate. In natural populations the equilibrium frequency for recessive
detrimental alleles is fairly low, because the mutation rate is low, but in
simulated evolution this can destroy adaptive progress.
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