"Josh Hayes"  wrote in message
news:cebk1a$10uu$1{at}darwin.ediacara.org...
> Francis Crick passes away at age 88.
>
> http://www.cbc.ca/cp/world/040729/w072972.html
>
> A sad, but not unexpected, day.

    "No one man discovered or created molecular biology.
     But one man dominates intellectually the whole field,
     because he knows the most and understands the most.
     Francis Crick."
- Jacques Monod, quoted by H.F. Judson in "The Eighth
   Day of Creation"

Crick's Nobel lecture:
http://www.nobel.se/medicine/laureates/1962/crick-lecture.html
presented at the height of the excitement over the genetic code,
provides a fairly good example of how theoretical concepts that
Crick generated interacted with the experimental results produced
by others.  Judson's book provides additional examples.  Crick's
influence was not always helpful, though.  In fact, our slowness in
noticing ribozymes, introns, and snoRNA can be blamed, in part,
on over-reliance on Crick's models.  Crick-style model construction
can be very useful as a guide for discovery experimentation, but
we should never forget that models can also be useful as a source
of ideas for paradigm-overthrow experiments.  Francis Crick would
certainly approve of this use of his ideas.
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