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Part 1 of 5
The Real Story
     Hydrazine Sulfate
     Article Extract from OPTIONS the alternative therapy book.
     by Richard Walters
     Hydrazine sulfate, a simple, off-the-shelf chemical, dramatically 
reverses cachexia
     (ka-KEK-si-a), the wasting-away process that kills two thirds of all 
cancer patients.
     This inexpensive drug, with little or no side effects, also has a 
clinically documented
     antitumor action. It causes malignant tumors to stop growing, to reduce 
in size, and,
     in some cases, to disappear. A growing number of cancer patients 
diagnosed as
     terminal have experienced tumor stabilization and remission through 
hydrazine
     sulfate therapy.
     About half of all patients who take hydrazine sulfate experience weight 
gain,
     restored appetite, extended survival time, and a significant reduction 
in pain and
     suffering. Many patients report an increase in vigor and strength and 
he
     disappearance of symptoms of the disease, along with feelings of 
well-being and
     optimism.
     While hydrazine sulfate may not be a sure-fire cancer cure, large-scale 
clinical trials
     suggest that it effects every type of tumor at every stage. It can be 
administered
     either alone or in combination with cytotoxic chemotherapy or radiation 
to make the
     cancer more vulnerable to these standard forms of treatment.
     Hydrazine sulfate is now undergoing Phase III trials sponsored by the 
National
     Cancer Institute. It is available to patients as a "compassionate IND 
(Investigational
     New Drug)," a designation conferred by the Food and Drug Administration 
on a
     case by case basis, so it is no longer, strictly speaking, an 
"unconventional therapy."
     Yet even though hundreds of patients across the country are using the 
drug, it is not
     widely discussed or disseminated among practicing physicians and its 
promise
     remains largely untapped twenty-four years after it was first proposed 
as an
     anticancer treatment by Dr. ]oseph Gold. Meanwhile, hydrazine sulfate is 
widely
     available in the Commonwealth of Independent States (formerly the Soviet 
Union),
     where researchers have followed up on Gold' s pioneering work with over 
ten years
     of investigation supporting the drug's effectiveness.
     "We've gone from a red lift to a yellow light, and hopefully will go to 
a green light,"
     says Dr. Gold, director of the Syracuse Cancer Research Institute in 
Syracuse,
     New York, which he founded in 1966. Since his discovery in 1968 that 
hydrazine
     sulfate can prevent the wasting-away process in cancer patients and 
inhibit tumor
     growth, Gold has waged courageous uphill battle to win acceptance for 
his nontoxic
     chemotherapy by the medical establishment.
     The American Cancer Society put hydrazine sulfate on its Unproven 
ethods
     blacklist in 1976. It condemned and stigmatized the drug following a 
clinical trial on
     twenty-nine patients at Memorial Sloan-Kettering Cancer Center in New 
York. But
     it is now widely acknowledged that the Sloan Kettering tests were 
botched.
     When Dr. Gold made an unannounced visit to the hospital in 1974, he 
discovered,
     to his horror, that "many patients in the study were either being 
underdosed or
     overdosed. Some people who were beginning to show anticachexia response 
were
     suddenly being given 90 to 100 milligrams at one time. All this was in 
clear violation
     of the drug protocols and of our joint agreements," said Gold. The 
study's protocol
     called for patients to receive 60 milligrams once a day for the first 
three days, twice
     a day for the next three days, and three times a day for the following 
six weeks.
     Therefore, some patients were getting a 67 percent overdose.
     In a letter of protest to Sloan Kettering, Gold pointed out that some 
patients were
     receiving a massive, single dose of approximately 120 to 190 milligrams 
a day
     (instead of the usual two or three 60 milligram doses), "which quickly 
wiped out
     whatever good response they were beginning to show." The study was so 
poorly
See part 2 of 5
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